Visitors Guide to the
Sikeston Depot Museum
116 West Malone Avenue
Sikeston, Missouri

Accessible Parking Accessible Picnic Facilities Accessible Interpretive Exhibits Accessible Missouri Historic Site Accessible Cultural Exhibits  Accessible Information Center Accessible Gift Shop Accessible Restrooms


Built as the Iron Mountain Railroad Train Depot in 1916, "The Depot" became a museum and cultural center in 2000. The Depot features dozens of permanent and rotating exhibits depicting the area's history and art. The history of railroads in Sikeston dates bate to 1853 when a group of businessmen from Arkansas, Kentucky, and Tennessee met in nearby Benton to form the Cairo Fulton Railroad. When John Sikes founded the town of Sikeston in 1860, he set aside property on the track thus assuring that Sikeston had a railroad depot. Sikeston was a supply depot of such importance in the Civil War that the track between Sikeston and Charleston were torn up to stop supplies from arriving in the area.  When the Cairo Fulton defaulted on bonds issued by the state of Missouri after the war, and ownership was transferred to the Iron Mountain Railroad. In 1916, the Iron Mountain began building the present depot.  Soon after the building was constructed, the line was acquired by the Missouri Pacific Railroad Company. It remained a Missouri Pacific station until the company merged with Union Pacific in 1982. The Sikeston Depot was closed in 1985 and the building was emptied, the windows boarded up, and the building became completely dormant.

In 1997, concerned citizens met to discuss revitalization of the Depot, forming the Sikeston Cultural Development Corporation and worked with the railroad and the School of the Ozarks to open the facility for community use. In 2000 the Sikeston Historical and Cultural Center (The Sikeston Depot Museum) opened to the public. The facility contains a historic museum section recounting the most important aspects of area culture, an exhibition hall where rotating and traveling exhibits are displayed, an art gallery featuring artists from different areas and disciplines, and a small community room where a video of Sikeston’s history is shown. The Depot was added to the National Register of Historic Places in 2000.

  Visiting the Sikeston Depot
          Tuesday - Saturday: 10 am - 4 pm
          Closed on Sundays and Mondays

There is no charge to visit the Sikeston Depot although donations are appreciated.
  Through February 27, 2019
The Sikeston Depot Museum has invited photographers to participate in its Regional Judged Photography Show to showcase their best images this judged exhibit. There are two divisions with prizes awarded: Adults (aged 19+) and a Youth Division (for photographers 18 and under). Acceptable photographs for the competition could fall into any one of these categories: Portrait/Genre, Floral Landscape, Abstract, or Animal/Wildlife. Most participating photographers are the Southeast Missouri region but some are former Sikeston area residents..
For more information visit the venue's website
Directions: The Sikeston Depot is located in the historic downtown district of Sikeston.
  GPS Coordinates
36° 52.561'
W 89° 35.381'
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