Visitors Guide to the
Bed & Breakfasts
and other accommodations
in the Mississippi River Meets the Ohio River Region
of the Middle Mississippi River Valley
Bellevue Bed and Breakfast
Cape Girardeau, MO
312 Bellevue Street
  The Bellevue Bed and Breakfast is a beautifully restored 1891 Queen Anne Victorian inn in Cape Girardeau, perfectly located in the heart of historic Old Town Cape. A short walk brings you to fine restaurants, the Mississippi River, antique shops, boutiques, art galleries, and the rest is history.
Boars Nest Bed & Breakfast
920 Kratzinger Hollow Road
Cobden, IL
  The Boars Nest Bed & Breakfast is located in the heart of the Shawnee Hills Wine Trail. Along with the beauty of the Shawnee National Forest, the Boars Nest welcomes you with five cabins in an environment that offers a peaceful view of the local woodlands and wildlife.
The Davie School Inn
300 Freeman Street
Anna, IL
  One of the largest B&B’s in Illinois, the Davie School Inn is housed in a remodeled 1910 public school building. The building has been restored and remodeling to create an Inn with all the modern conveniences yet still leave the atmosphere of the old school house.
Bruce Goff Castle
Bed & Breakfast

2375 Wing Hill Road
Cobden, IL
  Retreat from the outer world to a 25 acre kingdom, an American castle built by Hugh Duncan and designed by master architect Bruce Goff. Consider a bed and breakfast venture at a premiere organic architectural delight atop a forested bluff in the area of the Shawnee National Forest.
Hidden Lake Bed & Breakfast
433 Cook Avenue
Jonesboro, IL
  Hidden Lake B&B is situated on eighteen acres of woods, gardens and water in the midst of the Shawnee National Forest. Unseen from the house or the road is a “hidden” two-acre lake complete with a pier and great for fishing. Offered are four luxury suites, each with its own captivating theme.
Makanda Inn
855 Old Lower Cobden Road
Makanda, IL
  The Makanda Inn is an eco-friendly bed and breakfast on 18 wooded acres in the heart of southern Illinois.  It is conveniently located on the wine trail and close to Giant City State Park and has 4 suites in its main lodge and 3 cottages. The breakfasts are worth the stay alone.
Neumeyer's Bed & Breakfast
25 S. Lorimier Street
Cape Girardeau, MO
  Neumeyer’s Bed and Breakfast is in a century old unique Craftsman-style bungalow home and located within easy walking distance to the Mississippi riverfront and the downtown Cape Girardeau area. Our guests enjoy large rooms with cathedral ceilings, private baths, a refrigerator, wireless Internet access, satellite TV, and a full breakfast.
Oak Grove Cabin
Walnut Grove Cabins

Makanda, IL
  Oak Grove Cabins and Walnut Grove Cabins provide 5 private vacation cabins in Southern Illinois to accommodate your getaway to nature. Located in the heart of the Shawnee National Forest but just minutes south of Carbondale providing the perfect location to enjoy everything that Southern Illinois has to offer.
Peach Barn B&B
560 Chestnut Street
Alto Pass, IL
  Visit the Hedman Vineyards Winery and dine at the Peach Barn Cafe', serving authentic Swedish cuisine. Then spend the night at the Peach Barn Bed and Breakfast, for a peaceful nights rest housed within our old restored barn. The suite has two rooms furnished in Swedish style décor.
Rose Bed Inn
611 S. Sprigg Street
Cape Girardeau, MO
  Escape the worries of everyday life and get lost in the luxuries of our beautiful 1908 Victorian Styled home.  Here you will awake to the freshly brewed aroma of house blend coffee and hot breakfast treats.  Take advantage of being minutes away from the Mississippi River and Cape Girardeau’s Historic Downtown.
Sassafras Hill
730 Johnson Dairy Road
Dongola, IL
  Sassafras Hill is a family farm home located in the heart of Southern Illinois. Why settle for a one room rental cabin, when you can have a full sized house? Three bedrooms, two full bathrooms, a real kitchen with full-size appliances with all the comforts of home.
Shawnee Hill Bed & Breakfast
290 Water Valley Road
Cobden, IL
  Experience the tranquility of country living with antique furnished guestrooms, all with private baths and private decks. Star gaze and sip local wines, from the Shawnee Wine Trail, in an outdoor hot tub with a cozy fire and candles. There is so much to do, one weekend will not be enough.
Timber Ridge Inn
220 Timber Ridge Lane
Jonesboro, IL
  This rustic log cabin, one of the best cabins in Southern Illinois, is going to make you feel right at home. Timber Ridge Inn is nestled amid 80 wooded acres in the beautiful hills and valleys of Southern Illinois and perfect for hiking to biking to fishing and hunting.
Trail of Tears Lodge & Resort
1575 Fair City Road
Jonesboro, IL
  The multi-facetted facility is located in the wilds of the southernmost Illinois Ozarks surrounded by the Shawnee National Forest. The rustic Lodge, an original 1920 renovated barn has seven bedrooms and a restaurant. Outdoor amenities include a swimming pool, a stocked fishing pond, multi use trails, and horseback rentals.
406 E. Stoker Street
Carbondale, IL
618- 549-1717
  Searching for more than just a hotel room and a home away from home? We ensure that our guests have exactly that experience, by offering welcoming friendly service; personal attention to needs; home cooked hearty breakfasts; and clean, comfortable, cozy accommodation. Conveniently located near the Amtrak railway station.
Water Valley Inn
3435 Water Valley Road
Cobden, IL
  Built in 1922, the two-story farmhouse is located on one hundred beautiful acres in rural Southern Illinois and elicits the feeling of visiting Grandmas’ house down on the farm. The Inn is open year round to give you the opportunity to experience all the seasons that beautiful southernmost Illinois has to offer.
Windy Hill Acres Inn
830 Bell Hill Road
Cobden, IL

Are you looking for a quiet, out of the way place to rest, relax, and get away from it all?

The Potato House has two bedrooms, a spacious living room with a fireplace and a great view of the country side, and a kitchen with breakfast area. A Continental Breakfast is included.
Forest View Lodge
Jonesboro, IL
  1500 State Route 127 N
Mulberry Hollow Bed & Breakfast
Perryville, MO
  490 PCR 624
Shepherd's Inn
Clinton, KY
  416 N. Washington Street
Winetrail Cabins
Cobden, IL
  886 Mountain Glen Road
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